For the 31st H. Martin Friedman Lecture on April 7, 2016, esteemed Professor Gregory Petsko (Weill Cornell Medical College) will talk about “Targeting Protein Trafficking for the Treatment of Alzheimer’s Disease.” Associate Professor Contel publishes “Versatile Synthesis of Cationic N-Heterocyclic Carbene-Gold(I) Complexes Containing a Second Ancillary Ligand. Design of Heterobimetallic Ruthenium-Gold Anticancer Agents” in Chemical Communications. The Department of Chemistry is saddened by the loss of esteemed colleague and friend Professor Ira Levine. Professor Levine was an experienced and caring educator, and a wonderful mentor to faculty members and instructors. His textbooks have helped generations of chemistry students throughout the world. Read a remembrance of Professor Levine. The Department of Chemistry mourns the premature loss of our colleague and friend Professor Roberto Sánchez-Delgado. Our thoughts and deepest sympathy go out to his family. Read a remembrance of his many scientific accomplishments. Associate Professor Juszczak speaks about Scientific Uncertainty and Drug Development on the Macaulay Science Forward videos. Student Benjamin Rudshteyn mentioned in New York Post. Professor Sánchez-Delgado publishes “Synthesis of New 4-Aminoquinolines and Evaluation of Their In Vitro Activity against Chloroquine-Sensitive and Chloroquine-Resistant Plasmodium falciparum” in PLoS ONE Assistant Professor Czajkowska awarded a $470,ooo grant from the National Institutes of Health for the research project: “Theranostic nanoparticles for Dual Modality Cancer Therapy.” Associate Professor Contel publishes “Cyclometalated Iminophosphorane Gold(III) and Platinum(II) Complexes. A Highly Permeable Cationic Platinum(II) Compound with Promising Anticancer Properties” in the Journal of Medicinal Chemistry. The Chemistry Department welcomes new faculty member Assistant Professor Mariana Torrente. Assistant Professor Gallicchio publishes “A Unique Binding Mode of the Eukaryotic Translation Initiation Factor 4E for Guiding the Design of Novel Peptide Inhibitors” in Protein Science. Associate Professor Contel publishes “Design, synthesis and characterisation of new chimeric ruthenium(II)–gold(I) complexes as improved cytotoxic agents” in Dalton Transactions. Associate Professor Contel publishes “Heterometallic titanium-gold complexes inhibit renal cancer cells in vitro and in vivo” in Chemical Science. Don’t miss the 30th H. Martin Friedman Lecture this Thursday, May 14. Tom W. Muir (Princeton University) will talk about ultrafast “Houdini” proteins. Graduate student Danielle Hirsch is selected as a recipient of the WCC/Eli Lilly Travel Award to present her research at the Fall 2015 American Chemical Society National Meeting in Boston. Congratulations! Congratulations also to undergraduate student Sarah Avidan, recipient of the William H. Nichols Fellowship Award from the New York Local Section of the American chemical society. The Brooklyn College Science Retreat is coming soon on Friday, May 15! Assistant Professor Gallicchio publishes “BEDAM Binding Free Energy Predictions for the SAMPL4 Octa-Acid Host Challenge” in the Journal of Computer-Aided Molecular Design. Associate Professor Contel publishes “In vitro and in vivo Evaluation of Water-soluble Iminophosphorane Ruthenium(II) Compounds. A Potential Chemotherapeutic Agent for Triple Negative Breast Cancer” in the Journal of Medicinal Chemistry. Professor Greer is co-editor of the book The Chemistry of Peroxides, Vol. 3, John Wiley & Sons. Professor Greer publishes “Synergism Between Airborne Singlet Oxygen and a Trisubstituted Olefin Sulfonate for the Inactivation of Bacteria” in the journal Langmuir. Associate Professor Contel publishes “Organometallic Titanocene-Gold Compounds as Potential Chemotherapeutics in Renal Cancer. Study of their Protein KInase Inhibitory Properties” in the journal Organometallics. Associate Professor Juszczak publishes “The Broken Ring: Reduced Aromaticity in Lys-Trp Cations and High pH Tautomer Correlates with Lower Quantum Yield and Shorter Lifetimes” in the Journal of Physical Chemistry B. Assistant Professor Gallicchio awarded grant from the National Science Foundation for a project entitled “High Performance Software for Large-Scale Modeling of Binding Equilibria” Assistant Professor Gerona-Navarro publishes “Selective chemical modulation of gene transcription favors oligodendrocyte lineage progression” in Chemistry & Biology. Assistant Professor Gerona-Navarro awarded grant from the National Institutes of Health for a project entitled Chemical Probes Targeting Polycomb Repressive Complex 2 Gene Repression. Associate Professor Contel publishes “Luminescent iminophosphorane gold, palladium and platinum complexes as potential anticancer agents” in Inorganic Chemistry Frontiers. Assistant Professor Gallicchio publishes “Virtual Screening of Integrase Inhibitors by Large-scale Binding Free Energy Calculations: The SAMPL4 Challenge” in theJournal of Computer-Aided Molecular Design. Professor Sánchez-Delgado’s research selected as a Royal Society of Chemistry “Dalton Transactions Hot Article.” Associate Professor Juszczak’s research featured in Bachem PEPTalk. Professor Sánchez-Delgado publishes “Ruthenium nanoparticles supported on magnesium oxide: A versatile and recyclable dual-site catalyst for hydrogenation of mono- and poly-cyclic arenes, N-heteroaromatics, and S-heteroaromatics” in the Journal of Catalysis. Associate Professor Jarzecki publishes “Quantum mechanical investigation of aqueous desferrioxamine B metal complexes: Trends in structure, binding, and infrared spectroscopy” in the Journal of Inorganic Biochemistry. The Chemistry Department welcomes four new faculty: Assistant Professor Aneta Czajkowska, Assistant Professor Guillermo Gerona-Navarro, Assistant Professor Emilio Gallicchio and Lecturer Joann Mathias. Cancer research grant for Associate Professor Contel is featured in BC News. Associate Professor Contel awarded $1.4M grant from the National Institutes of Health for the study of “Titanium-gold based chemotherapeutics for prostate and kidney cancer.” Associate Professor Juszczak publishes “Relating Trp-Glu dipeptide fluorescence to molecular conformation: the role of the discrete chi 1 and chi 2 angles” in the Journal of Computational Chemistry. Associate Professor Jarzecki publishes “Mode Recognition in UV Resonance Raman Spectra of Imidazole: Histidine Monitoring in Proteins” in the Journal of Physical Chemistry B. The department awarded 53 bachelor’s degrees in chemistry. Congratulations to the Class of 2012! Best wishes in your future endeavors! Associate Professor Jarzecki publishes “Structural dependence of Mn complexation by siderophores: Donor group dependence on complex stability and reactivity” in Geochimica et Cosmochimica Acta. Professor Sanchez-Delgado publishes “Searching for New Chemotherapies for Tropical Diseases: Ruthenium-Clotrimazole Complexes Display High in Vitro Activity against Leishmania major and Trypanosoma cruzi and Low Toxicity toward Normal Mammalian Cells” in the Journal of Medicinal Chemistry. The paper is highlighted in Science-Business eXchange Congratulations to Nicholas Lease, who has been awarded a Division of Inorganic Chemistry Travel Award to present his results at the spring 2012 National ACS Meeting in San Diego. Associate Professor Jarzecki publishes “Trace Metal Complexation by the Triscatecholate Siderophore Protochelin: Structure and Stability” in BioMetals. Associate Professor Contel publishes “Luminescent Di- and Polynuclear Organometallic Gold(I)-Metal (Au2, {Au2Ag}n and {Au2Cu}n) Compounds Containing Bidentate Phosphanes as Active Antimicrobial Agents” in Chemistry – A European Journal. Graduate student Reena Rahi selected as associate chair of the 2012 Gordon Research Seminar in Inorganic Chemistry. Associate Professor Brenner-Moyer wins prestigious Faculty Early Career Development Award from the National Science Foundation.
