B.Sc. (honors), University of Salford (United Kingdom) (Biochemistry), 1977
Ph.D., University of Salford (United Kingdom) (Biochemistry), 1981
Lesley Davenport is been professor at Brooklyn College since 1998. Previously, Davenport served as executive officer for the Biochemistry Ph.D. Program, CUNY Graduate Center (2002-08); visiting research scientist, NIH (1995-96); visiting research fellow, Paterson Institute for Cancer Research & Medical Oncology, United Kingdom (1988-90); visiting summer research fellow, University of Utrecht, the Netherlands (1988); associate/assistant professor, Brooklyn College (1985-97); and associate research scientist (1984-85) and postdoctoral research fellow (1981-83), The Johns Hopkins University.
B.Sc. (honors), University of Salford (United Kingdom) (Biochemistry), 1977
Ph.D., University of Salford (United Kingdom) (Biochemistry), 1981
Desamero, J., and Davenport, L. (2020) 'Mapping Lateral Loop Conformational Switching of the Telomeric DNA G-Quadruplex on NMM Porphyrin Binding Using Fluorescent Guanine Analogs.' Biophysical Journal, 118 (3), Supplement 1, 65a.
Kopkalli, Y., Celius, T.C., Dickson-Karn, N.M., Davenport, L., Williams, B.W. (2019) 'The solvatochromic response of benzo[a]fluorenone in aprotic solvents compared with benzo[b]fluorenone and 9-fluorenone.' J. Physical Organic Chemistry, e3994.
Kopkalli, Y., M. Zamadar, D. Aebisher, A. Greer and L. Davenport. "Studies of Quadruplex Folding Using a New Fluorescent Porphyrin Derivative." Biophysical Journal 100.3, Supplement 1: 234a.
Liu, S.X., Y. Kopkalli, A.V. Smirnov, J.R. Knutson and L. Davenport. "Fluorescence Studies of Local Environmental Heterogeneity Around Guanine Residues of the Telomeric DNA Quadruplex Conformation." Biophysical Journal 100.3, Supplement 1: 234a.
Kopkalli, Y., M. Chery, B.W. Willliams and L. Davenport. "Benzo[b]Fluorenone as a Quadruplex Interactive Agent (Qia): Binding Studies and Quadruplex Formation With the Human Telomeric HT4 Sequence." Biophysical Journal Supplement 98.3: 265a.
Liu, X., Y. Kopkalli, A.V. Smirnov, T. Rosales, M.E. Hawkins, J.R. Knutson and L. Davenport. "Local Dynamic Studies of Guanine Residues Within the Human Telomeric DNA G-Quadruplexed Conformation." Biophysical Journal Supplement 98.3: 265a.
Rosales, T., X. Liu, Y. Kopkalli, L. Davenport, M. Hawkins and J.R. Knutson. "G-Quadruplex Folding Observed by Two Photon Fluorescence Correlation Spectroscopy and Dual Time Scale." Biophysical Journal Supplement 98.3: 414a.
Liu, X., Y. Kopkalli and L. Davenport. "Conformational Stabilization of G-quadruplex DNA by Metalloporphyrins." Biophysical Society Meeting Abstracts, Biophysical Journal Supplement: 344a.
Liu, X.L., Y. Kopkalli, T. Vu, M.E. Hawkins and L. Davenport. "Conformational Stability of Fluorescently Labeled Human Telomeric G-Quadruplexed DNA Sequences." Biophysical Journal 94: 289a.
Martinez, A., Ch. S.K. Rajapakse, B. Naoulou, Y. Kopkalli, L. Davenport and R.A. Sanchez-Delgado. "The Mechanism of Antimalarial Action of the Ruthenium(II)-Chloroquine Complex [RuCl2(CQ)]2." Journal of Biological Inorganic Chemistry DOI 10.1007/s00775-008-0356-9.
Martinez, A., Rajapakse, Ch. S. K., Naoulou, B., Kopkalli, Y., Davenport, L. and Sanchez-Delgado, R.A. (2008) 'The Mechanism of Antimalarial Action of the Ruthenium(II)-Chloroquine Complex [RuCl2(CQ)]2.' Journal of Biological Inorganic Chemistry 13, 703-712.
Rosales, T., J. Xu, A.V. Smirnov, C. Combs, L. Davenport and J.R. Knutson. "Simultaneous Imaging of NAD+ and NADH Using CARS and 2-Photon Fluorescence Microscopy." Biophysical Journal 90S: 156a.
Davenport, L., A.V. Smirnov, C.A. Combs, K. Blinova, J.R. Knutson and R.S. Balaban. "Fluorescence Lifetime Imaging of NADH in Cells, in Solution and Encapsulated in Lipid Vesicles." Biophysical Journal 90S: 147a.
Kopkalli Y., M.J. Rosen and L. Davenport. "Interaction of N-Alkyl-2-Pyrrolidinone Surfactants with DMPC Lipid Bilayers." Biophysical Journal 90S: 505a.
Jamison, J.L., L. Davenport and B. Williams. 'Solvatochromic in the Aromatic Ketone Benzo(b)Fluorenone.' (2006), Chemical Physics Letters, 422: 30-35.
Kopkalli, Y., M.J. Rosen and Lesley Davenport. "Interactions of N-alkyl-2-Pyrrolidinone Surfactants with Dimyristoyilphosphatidylcholine Small Unilamellar Vesicles." Biophysical Journal 88, 70a, Abstract.
Kopkalli, Yasemin, Milton J. Rosen and Lesley Davenport. "Interactions of N-alkyl-2-pyrrolidinone Surfactants with Lipid Bilayers." Department of Chemistry, CUNY Graduate Center and Brooklyn College. Abstracts of Papers, 229th ACS National Meeting. San Diego, March 13-17, PHYS-489. Washington, D.C.: American Chemical Society. CODEN: 69GQMP Conference; meeting Abstract written in English. AN 2005:193605 CAPLUS (Copyright (c) 2006 ACS on SciFinder (R)).
Ramsook, C. and Lesley Davenport. "Effect of Guanidine Hydrochloride and Urea on the Conformation of BPAO." Bilophysical Journal 88, 38a, Abstract.
Voloshchuk, N., M.E. Hawkins and Lesley Davenport. "Mapping the DNA Binding Site of HIV-1 Integrase Using Fluorescent Oligonucleotides and Fluorescence Polarization." Biophysical Journal 88: 406a.
Mathias, J.H., Rosen, M.J., and Davenport, L. 'Fluorescence Study of Premicellar Aggregation in Cationic Gemini Surfactants.' Langmuir (2001), 17, 6148-6154.
Rosen, M.J., Mathias, J.H., and Davenport, L. 'Aberrant Aggregation Behavior in Cationic Gemini Surfactants Investigated by Surface Tension, Interfacial Tension, and Fluorescence Methods.' Langmuir (1999) 15, 7340-7346.
Targowski, P., and Davenport, L. 'A Direct Method for Correction of Pressure-Induced Scrambling of Polarized Fluorescence Intensities.' Analytical Biochemistry (1999) 274, 249-263.
"Collaborator" Proposal Contributor (Conformation and Dynamics of Biological Macromolecules: G-Quadruplexed DNA). MRI proposal: "Acquisition of a Streak Camera System for Time-resolved Deep UV-visible Photoluminescence Spectroscopy." PI: Mim Nakarmi (Dept. Physics, Brooklyn College).
Service Recognition, Royal Society of Chemistry - US Section
NIH-SCORE (SC3 GM095437-02), for "Conformation and Multimeric Formation of G-Quadruplexed DNA: Effects of Ligand Interactions." March 1, 2016 - Feb. 28, 2017.
"Occasional User" Proposal Contributor (Conformational Studies of Human G-Quadruplexed DNA Under Molecular Crowding Conditions) for NSF MRI: "Proposal for a Stimulated-Emission-Depletion (STED) Microscope." PI: Rein Ulijn (ASRC).
NIH-SCORE (SC3 GM095437-02), for "Conformation and Multimeric Formation of G-Quadruplexed DNA: Effects of Ligand Interactions." March 1, 2015 - Feb. 28, 2016.
NIH-SCORE (SC3 GM095437-02), for "Conformation and Multimeric Formation of G-Quadruplexed DNA: Effects of Ligand Interactions." March 1, 2014 - Feb. 28, 2015.
NIH-SCORE (SC3 GM095437-02), for "Conformation and Multimeric Formation of G-Quadruplexed DNA: Effects of Ligand Interactions." March 1, 2013 - Feb. 28, 2014.
NIH-SCORE (SC3 GM095437-02), for "Conformation and Multimeric Formation of G-Quadruplexed DNA: Effects of Ligand Interactions." March 1, 2012 - Feb. 29, 2013.
NIH-SCORE (SC3 GM095437-01), for "Conformation and Multimeric Formation of G-Quadruplexed DNA: Effects of Ligand Interactions." March 1, 2011 - Feb. 29, 2012.
"Other User" Proposal Contributor (Studies of Ligand Binding with Quadruplexed-DNA.) for NSF MRI-R2 Proposal for Major Research Instrument: "Acquisition of a Plasmon Resonance Spectrometer." PI: Peter Lipke, Biology Department, Brooklyn College (funded 2010-2013).
NIH-MBRS SCORE (1S06 GM060654 (076168)-010001), for "Conformational Stability and Dynamics of G-Quadruplexed DNA and Ligand Interactions." The specific aims of this project are: 1) to map the conformational stability at specific sites within the G-quadruplex and to assess the effects of QIA binding on these parameters; and 2) to examine the underlying dynamics of intramolecular G-quadruplex folding and unfolding. April 1, 2010-March 31, 2011.
NIH-MBRS SCORE (1S06 GM060654 (076168)-010001), for "Conformational Stability and Dynamics of G-Quadruplexed DNA and Ligand Interactions." The specific aims of this project are: 1) to map the conformational stability at specific sites within the G-quadruplex and to assess the effects of QIA binding on these parameters; and 2) to examine the underlying dynamics of intramolecular G-quadruplex folding and unfolding. April 1, 2009-March 31, 2010.
Subcontractor for Collaborative Research-RUI: "Solvatochromic Benzofluorenone Compounds as "Self-Reporting" Quadruplex DNA Interactive Agents." PI: Williams (Bucknell University) and Celius (Ohio Northern University) (2010-2013)
Broeklundian Professor, Brooklyn College, Fall 2003 - Spring 2008.
Editorial board, Spectroscopy, 2000-present.
NIH-MBRS SCORE, (1S06 GM060654 (076168)-010001), for "Conformational Stability and Dynamics of G-Quadruplexed DNA and Ligand Interactions." The specific aims of this project are: 1) to map the conformational stability at specific sites within the G-quadruplex and to assess the effects of QIA binding on these parameters; and 2) to examine the underlying dynamics of intramolecular G-quadruplex folding and unfolding. April 1, 2008-March 31, 2009.
NIH-MBRS SCORE, (1S06 GM060654 (076168)-010001), for "Conformational Stability and Dynamics of G-Quadruplexed DNA and Ligand Interactions." The specific aims of this project are: 1) to map the conformational stability at specific sites within the G-quadruplex and to assess the effects of QIA binding on these parameters; and 2) to examine the underlying dynamics of intramolecular G-quadruplex folding and unfolding. April 1, 2007-March 31, 2008.
NIH-MBRS SCORE, (1S06 GM060654 (076168)-010001), for "Conformational Stability and Dynamics of G-Quadruplexed DNA and Ligand Interactions." The specific aims of this project are: 1) to map the conformational stability at specific sites within the G-quadruplex and to assess the effects of QIA binding on these parameters; and 2) to examine the underlying dynamics of intramolecular G-quadruplex folding and unfolding. April 1, 2006-March 31, 2007.
Outstanding Service Award, New York Section of the American Chemical Society
Outstanding Woman Scientist Award, New York Academy of Sciences and MetroSection of AWIS.
Chair and Service Award, New York Section of the American Chemical Society.
Claire and Leonard Tow Professorship, Brooklyn College, 2000-02.
Davenport, L. (PI) PSC-CUNY Grant Award - Year 2. "Conformational Studies of Bovine Plasma Amine Oxidase." $3,923 (7/1/2001 - 6/30/2002)
Davenport, L. (PI) PSC-CUNY Grant Award - Year 1. "Conformational Studies of Bovine Plasma Amine Oxidase." $5,026 (7/1/2000 - 6/30/2001)
Davenport, L. 'G-Quadruplex Binding Assay and Compounds Therefor'. (2017) US Patent No. 9,598,719.
Celius, T.C., Karn, N.M., Williams, B.W., Davenport, L., Black, R.J., and Napoli, J. 'Exploration of Solvatochromism in 9-Fluorenone Derivatives Using Steady-State and Time-Resolved Spectroscopies.' (2021) Spring Annual American Chemical Society Meeting, Poster Presentation.
Desamero, J., and Davenport, L. 'Conformational Binding of N-Methyl Mesoporphyrin IX with Model Telomeric DNA G-Quadruplex Forming Sequences.' (2021), Fall Annual American Chemical Society Meeting, Poster Presentation.
Desamero, J., and Davenport, L. (2020) 'Mapping Lateral Loop Conformational Switching of the Telomeric DNA G-Quadruplex on NMM Porphyrin Binding Using Fluorescent Guanine Analogs.' Annual Biophysical Society Meeting, Poster Presentation.
Nicolas Copernicus University, Torun, Poland. "International Symposium Honoring the Scientific Contributions of Professor Andrezj Kowlaczyck". L. Davenport (Invited Speaker), 'Planar Fluorescent Molecules for Biological Applications'.
East China National University, China. International Symposium on: "Laser and Computational Biophysics". L. Davenport (Invited Speaker), 'Investigating G-Quadruplex DNA Conformations Using Fluorescence Spectroscopy.'
Kopkalli, Y., M. Zamadar, D. Aebisher, A. Greer and L. Davenport. "Studies of Quadruplex Folding Using a New Fluorescent Porphyrin Derivative" poster. Annual Biophysical Society Meeting.
Liu, S.X., Y. Kopkalli, A.V. Smirnov, J.R. Knutson and L. Davenport. "Fluorescence Studies of Local Environmental Heterogeneity Around Guanine Residues of the Telomeric DNA Quadruplex Conformation" poster. Annual Biophysical Society Meeting.
"Conformational Studies of G-Quadruplexed DNA." CUNY Structural Biology Workshop. June.
"DNA Knots and Tumorigenesis: Folding and Conformation of Quadruplex-DNA." Institute of Biotechnology, St John's University. New York, September.
Kopkalli, Y., M. Chery, B.W. Willliams and L. Davenport. "Benzo[b]Fluorenone as a Quadruplex Interactive Agent (Qia): Binding Studies and Quadruplex Formation With the Human Telomeric HT4 Sequence" poster. Annual Biophysical Society Meeting.
Liu, X., Y. Kopkalli, A.V. Smirnov, T. Rosales, M.E. Hawkins, J.R. Knutson and L. Davenport. "Local Dynamic Studies of Guanine Residues Within the Human Telomeric DNA G-Quadruplexed Conformation" poster. Annual Biophysical Society.
Rosales, T., X. Liu, Y. Kopkalli, L. Davenport, M. Hawkins and J.R. Knutson. "G-Quadruplex Folding Observed by Two Photon Fluorescence Correlation Spectroscopy and Dual Time Scale." Annual Biophysical Society Meeting.
"DNA Knots and Tumorigenesis: Folding and Conformation of Quadruplex-DNA." Chemistry Department, Bucknell University. Lewisburg, Pa., April.
Chery, M., Y. Kopkalli, B.W. Williams and L. Davenport. "Formation and Stabilization of G-Quadruplex DNA Structures With Benzo[b]Fluorenone" poster. Annual ABRCM meeting.
Liu, X., Y. Kopkalli and L. Davenport. "Conformational Stabilization of G-quadruplex DNA by Metalloporphyrins" poster. Annual Biophysical Society Meeting.
Liu, X.L., Y. Kopkalli, T. Vu, M.E. Hawkins and L. Davenport. "Conformational Stability of Fluorescently Labeled Human Telomeric G-Quadruplexed DNA Sequences" poster. Annual Biophysical Society Meeting. Long Beach, Calif.
Chemistry Department Appointments Committee Member, Fall 2017-Spring 2023
Chemistry Department Equipment Committee, Fall 2017 - Spring 2021.
Chemistry Department Integrity Committee (2013-2021)
Chemistry Department Student Awards and Recognition Committee, Spring 2017-Spring 2021.
Elected Alternate Member of the Brooklyn College Policy Council, Sept 2019 - May 2021.
Elected Member of Faculty Council representing the School of NBS, Fall 2012-Spring 2021.
Honorable Treasurer, US Section of the Royal Society of Chemistry (2008-2021).
Member, Research Foundation-Faculty Advisory Committee, University Faculty Senate, CUNY (2015-2021)
Board Member, The Research Foundation of CUNY (2017-2021)
Brooklyn College Faculty Program Coordinator - NSF Funded CUNY NYC Louis Stokes Alliance for Minority Participation (LSAMP) Program (9/1/2018-8/31/2023)
Elected Graduate Faculty Council Representative for the Biochemistry PhD Program, Fall 2016 - Spring 2020
Member, Blavatnik Regional Awards Jury, New York Academy of Sciences (2016-2020)
Member, Programs Task Force, Department of Chemistry, Fall 2020 - Spring 2021
Member, Presidential Advisory Committee on Distinguished Professors (2013 - 2016).
Advisory Board Member, Executive Committee for the CUNY-Center for Advanced Technology (CAT) (Fall 2014 - Spring 2015)
NIH-Enabling Biomedical Technologies Study Section Ad Hoc Panel Member.
Chairperson (Summer Session I), Department of Chemistry, Brooklyn College of CUNY
Chairperson (Summer Session II), The Department of Chemistry, Brooklyn College of CUNY
Deputy Chair, Department of Chemistry, Brooklyn College (Spring 2011- Spring 2014)
Panel discussant, CUNY Inspiring Woman Scientists Forum, September.
Chair, Faculty Membership Committee, Biochemistry PhD Program, CUNY Graduate Center (2002-2008)
Executive Officer, Biochemistry Ph.D. Program, CUNY Graduate Center, 2002-2008.
Student Academic Appeals Committee, The Graduate Center, CUNY
Councilor representing the New York Section, American Chemical Society, 2003-05.
Public Relations Committee, Department of Chemistry (Fall 2005 - Spring 2007)
Affiliate member, National Committee on Science, American Chemical Society.
Chair, New York Section of the American Chemical Society.
Deputy Executive Officer, Biochemistry PhD Program, CUNY Graduate Center (1985-2002)
Chair, Biological Fluorescence Spectroscopy Subgroup, Biophysical Society.
Coordinator, Annual Brooklyn College Science Day, 1997-2000
Organizer: Annual Brooklyn High School Day (in partnership with the Brooklyn Subsection of the NY Section of the American Chemical Society) (1997-2000)
Chair-Elect, Biological Fluorescence Spectroscopy Subgroup, Biophysical Society.
Initiated and Served as Program Coordinator for the Biochemistry & Chemistry Doctoral Student Seminar Program at Brooklyn College. (Spring 2006 - Fall 2010; except Spring 2009 and Spring 2010 semesters when on fellowship leave).
Editorial Board Member, Biomedical Spectroscopy & Imaging
ABRCMS Meeting (San Antonio) - Judge for the Biochemistry Division Student Research Posters.
ABRCMS Meeting (San Jose) - Judge for the Biochemistry Division Student Research Posters.
Member, editorial board, Spectroscopy.
Panel Member, NIH Study Section "Enabling Biomedical Technologies", 2007-2011.